Crizotinib

Crizotinib

Product Details:

  • Taste Bitter
  • Structural Formula C21H22Cl2FN5O (Structure involves a pyrazolopyrimidine core with chlorinated and fluorinated substituents)
  • Color Off-white to yellow
  • Molecular Weight 450.34 g/mol
  • Solubility Slightly soluble in water soluble in DMSO and methanol
  • Melting Point 215-225C
  • Ph Level Neutral or slightly acidic depending on solubility medium
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Crizotinib Product Specifications

  • NMT 10 m
  • 0.5%
  • Store in a cool dry place away from light and moisture
  • Pharmaceutical API
  • Medical Grade
  • 2 years if stored properly
  • Non-poisonous in the prescribed amounts
  • 0.001%
  • 2933.99.97
  • Off-white to yellow crystalline powder
  • Neutral or slightly acidic depending on solubility medium
  • Data not available
  • Odorless
  • Powder
  • C21H22Cl2FN5O
  • 450.34 g/mol
  • 215-225C
  • Slightly soluble in water soluble in DMSO and methanol
  • 99%
  • Off-white to yellow
  • Used in the treatment of non-small cell lung cancer (NSCLC) by inhibiting ALK and ROS1-positive cancerous cells
  • Crizotinib
  • Crizotinib
  • 877399-52-5
  • C21H22Cl2FN5O (Structure involves a pyrazolopyrimidine core with chlorinated and fluorinated substituents)
  • Bitter

Product Description

CAS number: 877399-52-5

Certificate: ISO CERTIFICATE,GMP,FACTORY GMP,WHO GMP,USFDA,EUGMP,GMP-SFDA,cGMP,PRODUCT GMP,Cofepris Mexico,Halal,Kosher,Korea FDA

Properties :

Synonym

3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-Pyridinamine

Molecular Formula

C21H22Cl2FN5O

Molecular Weight

450.343

Specifications

AVAILABLE ON REQUEST

Packing

EXPORT WORTHY PACKING

Availability

FOR R&D PURPOSE ONLY

Related Intermediates :

Intermediate Name

CAS Number

(S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol

877397-65-4

(R)-1-(2,6-Dichloro-3-fluorophenyl)ethanol

330156-50-8

[5-Bromo-3-[(1R)-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridin-2-yl]amine

877399-00-3

4-(4-Bromopyrazol-1-yl)piperidine-1-carboxylic acid tert-butyl ester

877399-50-3

tert-Butyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate

877399-74-1

tert-Butyl 4-(4-iodo-1H-pyrazol-1-yl)piperidine-1-carboxylate

877399-73-0


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