Crizotinib

Product Details:

Heavy Metal (%) 0.001%
Solubility Slightly soluble in water soluble in DMSO and methanol
Loss on Drying 0.5%
Shelf Life 2 years if stored properly
Smell Odorless
Boiling point Data not available
Taste Bitter
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Crizotinib Product Specifications

HS Code 2933.99.97
Usage Used in the treatment of non-small cell lung cancer (NSCLC) by inhibiting ALK and ROS1-positive cancerous cells
CAS No 877399-52-5
Physical Form Powder
Color Off-white to yellow
Structural Formula C21H22Cl2FN5O (Structure involves a pyrazolopyrimidine core with chlorinated and fluorinated substituents)
Storage Store in a cool dry place away from light and moisture
Type Pharmaceutical API
Particle Size NMT 10 m
Poisonous Non-poisonous in the prescribed amounts
Medicine Name Crizotinib
Appearance Off-white to yellow crystalline powder
Grade Medical Grade
Melting Point 215-225C
Molecular Formula C21H22Cl2FN5O
Ph Level Neutral or slightly acidic depending on solubility medium
Molecular Weight 450.34 g/mol
Loss on Drying 0.5%
Heavy Metal (%) 0.001%
Solubility Slightly soluble in water soluble in DMSO and methanol
Shelf Life 2 years if stored properly
Boiling point Data not available
Taste Bitter
Smell Odorless
Chemical Name Crizotinib
Purity(%) 99%

Product Description

CAS number: 877399-52-5 Certificate: ISO CERTIFICATE,GMP,FACTORY GMP,WHO GMP,USFDA,EUGMP,GMP-SFDA,cGMP,PRODUCT GMP,Cofepris Mexico,Halal,Kosher,Korea FDA Properties : Synonym 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-Pyridinamine Molecular Formula C21H22Cl2FN5O Molecular Weight 450.343 Specifications AVAILABLE ON REQUEST Packing EXPORT WORTHY PACKING Availability FOR R&D PURPOSE ONLY Related Intermediates : Intermediate Name CAS Number (S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol 877397-65-4 (R)-1-(2,6-Dichloro-3-fluorophenyl)ethanol 330156-50-8 [5-Bromo-3-[(1R)-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridin-2-yl]amine 877399-00-3 4-(4-Bromopyrazol-1-yl)piperidine-1-carboxylic acid tert-butyl ester 877399-50-3 tert-Butyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate 877399-74-1 tert-Butyl 4-(4-iodo-1H-pyrazol-1-yl)piperidine-1-carboxylate 877399-73-0

FAQs of Crizotinib:

Q: What is the physical form of Crizotinib?

A: Crizotinib is available in a powder form.

Q: What is the usage of Crizotinib?

A: Crizotinib is used in the treatment of non-small cell lung cancer (NSCLC) by inhibiting ALK and ROS1-positive cancerous cells.

Q: What is the shelf life of Crizotinib?

A: Crizotinib has a shelf life of 2 years if stored properly.

Q: How should Crizotinib be stored?

A: Crizotinib should be stored in a cool, dry place away from light and moisture.

Q: What is the purity specification of Crizotinib?

A: Crizotinib has a purity specification of 99%. ```

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